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UCSF Endocrine Neoplasia Destination Center


The UCSF Endocrine Neoplasia Destination Center offers access to multidisciplinary thought leaders and world experts in endocrine surgery and endocrine neoplasia, who have extensive, high-volume experience in all aspects of patient care. Adult and pediatric patients gain access to collaborative multi-disciplinary team care guided by monthly expert tumor boards for adrenal, thyroid, parathyroid, and pancreatic neuroendocrine diseases.


  • Same day thyroid and parathyroid surgery
  • Minimally invasive parathyroidectomy
  • Intraoperative PTH monitoring
  • Minimal access thyroid surgery
  • Cranial nerve and recurrent laryngeal nerve neuromonitoring during surgery
  • Continuous vagal stimulation during surgery for voice monitoring
  • Comprehensive surgical treatment for locoregional metastatic disease of thyroid cancer
  • Minimally invasive adrenalectomy with 23hour admit or ambulatory, if possible
  • Posterior retro-peritoneal adrenalectomy (PRA)
  • Laparoscopic adrenalectomy
  • Open adrenalectomy for cancer
  • Minimally invasive (laparoscopic and robotic) pancreatic surgery
  • Spleen & vessel preserving minimally invasive pancreatic resection
  • Minimally invasive laparoscopic and robotic) hepatic surgery
  • Re-operative surgery for failed or recurrent endocrine disease
  • Endocrine surgery for children of any age in our comprehensive pediatric endocrine neoplasia multidisciplinary center


Parathyroid disease

  • Sestamibi/ SPECT for parathyroid disease
  • 4D CT for parathyroid disease
  • 18-F Fluorocholine PET/MRI scan for parathyroid disease

Adrenal disease

  • DOTATATE-CT PET for pheochromocytoma and paraganglioma
  • PET scan
  • EUS

Pancreatic disease

  • 4D CT for Pancreatic pathology
  • DOTATE-CT PET for Pancreatic Neuroendocrine Tumors


Thyroid disease

  • FNA with molecular testing
  • I 123 scanning
  • Dosimetry for RAI
  • RFA and ethanol ablation of metastatic cervical LNs and some selected thyroid nodules

Adrenal disease

  • Selective adrenal vein sampling

Parathyroid disease

  • Selective venous sampling for parathyroid disease with rapid PTH monitoring

Pituitary disease

  • IPSS
  • Dynamic contrast enhanced imaging of the pituitary

Pancreatic disease

  • Endoscopic Ultrasound (EUS) for tumor localization & biopsy


Thyroid disease

  • UCSF 500: genomic profiling

Adrenal disease

  • Low-dose ACTH stimulation test
  • Traditional ACTH stimulation test
  • Confirmatory testing for primary hyperaldosteronism:
    • Oral salt load testing
    • Saline infusion
  • UCSF 500: genomic profiling

Parathyroid disease

  • Calcium challenge testing

Pancreatic disease

  • Pancreatic neuroendocrine tumor functional testing

Other endocrine disease

  • Glucagon stimulation test for growth hormone deficiency
  • Formal water deprivation test.
  • Inpatient 72 hour fasting glucose monitoring
  • Infusion centers


  • Comprehensive care and testing for children and adults with endocrine neoplasia genetic syndromes
  • Multidisciplinary team for endocrine neoplasia with active tumor boards: endo, endo surg, rads/nuclear medicine, pathology, ENT, medical oncology, radiation oncology, pediatric
  • Comprehensive Voice Restoration clinic
  • Diabetes teaching center
  • Genetic counseling for pediatric and adult patients
  • Re-sensitization therapy for iodine refractory thyroid cancer (with oncology involvement)
  • Azedra therapy for metastatic pheo/paragangliomas (Lutethera off label)
  • Novel chemotherapeutic and small molecule therapies for locally advanced and metastatic endocrine cancers based on personalized testing, including neoadjuvant treatments


  • Access to enrollment in registries to provide patient-facing information about thyroid cancer, including patient reported outcomes
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